Microneedle developed from technology of Endoderma
TECHNOLOGY #1_Cross-linked HA
One time application for the long lasting moisturizing effect up to 7 days!!
1 Hour Swelling Ratio: 6x increase
Degraded dramatically after
1 Hour Swelling Ratio: 25x increase
Maintain Swelling even after 5 hours
* Efficacy can last up to 7 days
depending on the individuals
Hyaluronic acid, HA
Cross-linked hyaluronic acid
TECHNOLOGY #2_Endoderma™ Microneedle Shape
Active Ingredient Delivery Rate
Other Companies’ Microneedle
The genuine Microneedle of Endoderma designed to completely improve the weaknesses of various conventional TDDS
based on the proprietary TDDS can deliver the active ingredients into the skin without pain
After having made hundreds of experimental attempts, Endoderma has successfully developed the genuine microneedle that can effectively deliver the active ingredients into the skin through its unique shape and optimal array of microneedle
Does not deform when attached to the skinIt can effectively deliver to the dermis layer.
Optimal shape and size of microneedleTip
For the best delivery rate (delivery of more than 80% of active ingredients)
Hexagonal array, spacing
For best effect (mechanical strength) + minimum irritation
Microneedle optimal aspect ratio
TECHNOLOGY #3_Fully Manufacturing Automated Process
Best Quality Control and Quality Assurance system
By 3D Vision Inspection system
Mix active ingredients
Pour mixed APIs
on mold plate
Remove bubbles and dry
Cut dried hydrocolloid
to desired shape
3D Vision Inspection
Dispensing of raw materials
Patch shape fabrication unit
Line Scanner / 2D 3D Inspection
Microneedle of Endoderma is manufactured by a fully-automated system that focuses on quality and sanitary control for the high quality of the product.
The latest technology of the 2D/3D Vision Inspection System makes comprehensive QA/QC management possible by checking the height, array, and location of microstructures and any possible contaminants in all final products.
Dissolution test after applying Micro Patch
After 10 sec.
After 30 min.
After 120 min.